How I arm and spec the powers of my three fav classes for both Single player and multi-player.

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For Commander Shepard in single player:

Infiltrator: Primary Weapon: N7 Valiant with Concentration Mod and Extended Barrel Mod Seconday Weapon: N7 Hurricane with Ultralight Materials and High Caliber Barrel

Powers: Tactical Cloak: Rank 4 Damage increase, Rank 5 Recharge speed increase, Rank 6 Damage increase Cryo Ammo: Rank 4 Squad Bonus, Rank 5 Ammo Capacity, Rank 6 Damage Combo Disruptor Ammo: Rank 4 Squad Bonus, Rank 5 Ammo Capacity, Rank 6 Stun Sticky Grenade: Rank 4 Radius, Rank 5 Armor-Piercing, Rank 6 Proximity Trap Incinerate: Rank 4 Impact Radius, Rank 5 Recharge speed, Rank 6 Armor Damage Sabotage: Rank 4 Duration, Rank 5 Recharge Speed, Rank 6 Berserk Fitness: Rank 4 Durability, Rank 5 Shield Recharge, Rank 6 Durability Operational Mastery: Rank 4Influence and Duration, Rank 5 Weight Capacity, Rank 6 Sniper damage.

Bonus Power: Armor Piercing Ammo: Rank 4 Squad Bonus, Rank 5 Ammo Capacity, Rank 6 Pierce

Engineer: Primary Weapon: N7 Eagle with High Caliber Barrel and Magazine Upgrade Secondary Weapon: N7 Hurricane with Ultralight Materials and High Caliber Barrel

Powers Incinerate: Rank 4 Impact Radius, Rank 5 Recharge speed, Rank 6 Armor Damage Overload: Rank 4 Chain Overload, Rank 5 Neural Shock, Rank 6 Chain Overload Cryo Blast: Rank 4 Radius, Rank 5 Speed Reduction, Rank 6 Recharge Speed Combat Drone: Rank 4 Detonate, Rank 5 Shock, Rank 6 Chain Lightning Sentry Turret: Rank 4 Shields and Damage, Rank 5 Armor-Piercing Ammo, Rank 6 Rockets. Sabotage: Rank 4 Duration, Rank 5 Recharge Speed, Rank 6 Berserk Fitness: Rank 4 Durability, Rank 5 Shield Recharge, Rank 6 Durability Tech Mastery: Rank 4 Power Damage, Rank 5 Damage and Capacity, Rank 6 Drone Mastery

Bonus Power: Defense Drone: Rank 4 Range, Rank 5 Damage and Range, Rank 6 Chain Lightning

Soldier: Primary Weapon: M-96 Mattock with Magazine Upgrade and Extended Barrel Secondary Weapon: Geth Plasma Shotgun with High Caliber Barrel and Smart Choke. Next Weapon: M-13 Raptor with Piercing Mod and Extended Barrel Next Weapon: N7 Hurricane with High Caliber Barrel and Magazine Upgrade Next Weapon: N7 Eagle with High Caliber Barrel and Magazine Upgrade Powers: Adrenalin Rush: Rank 4 Hardening, Rank 5 Duration, Rank 6 Shield Boost Concussive Shot: Rank 4 Radius, Rank 5 Recharge speed, Rank 6 Amplification Frag Grenade: Rank 4 Radius, Rank 5 Max Grenades, Rank 6 Armor-Piercing Cryo Ammo: Rank 4 Squad Bonus, Rank 5 Ammo Capacity, Rank 6 Damage Combo Disruptor Ammo: Rank 4 Squad Bonus, Rank 5 Ammo Capacity, Rank 6 Stun Incendiary Ammo: Rank 4 Squad Bonus, Rank 5 Ammo Capacity, Rank 6 Explosive Burst. Fitness: Rank 4 Durability, Rank 5, Martial Artist, Rank 6 Fitness Expert Combat Mastery: Rank 4 Influence and Duration, Rank 5 Squad Bonus, Rank 6 Weapon Master

Bonus Power: Defense Matrix: Rank 4 Durability, Rank 5 Shield Recharge, Rank 6 Durability

Multi-Player

Human Infiltrator: Primary Weapon: Black Widow with Heavy Barrel and Spare Thermal Clip Secondary Weapon: None

Tactical Cloak: Rank 4 Damage, Rank 5 Recharge Speed, Rank 6 Sniper Damage Cryo Blast: Not taken Sticky Grenade: Rank 4 Radius, Rank 5 Armor-Piercing, Rank 6 Proximity Trap Fitness: Rank 4 Durability, Rank 5 Shield Recharge, Rank 6 Fitness Expert

Equipment: Ammo Bonus: Any except Armor Piercing Weapon Bonus: Sniper Rifle Rail Amp Armor Bonus: Adrenalin or Power Efficiency Mod

Human Engineer: Primary Weapon: Phalanx with Armor Piercing and Scope

Powers: Combat Drone: Rank 4 Detonate, Rank 5 Shock, Rank 6 Chain Lightning Incinerate: Rank 4 Impact Radius, Rank 5 Recharge speed, Rank 6 Armor Damage Overload: Rank 4 Chain Overload, Rank 5 Neural Shock, Rank 6 Chain Overload Alliance Training: Rank 4 Damage and Capacity, Rank 5 Power Damage, Rank 6 Not taken Fitness: Only to Rank 3

Equipment: Ammo Bonus: Any but Armor Piercing Weapon Bonus: Pistol Rail Amp Armor Bonus: Power Amplifier

Human Soldier: Primary Weapon: M-37 Falcon with Heavy Barrel and Magazine Upgrade Secondary Weapon: Geth Plasma Shotgun with Shredder Mod and High Spare Thermal Clip

Powers: Adrenalin Rush: Rank 4 Hardening, Rank 5 Duration, Rank 6 Shield Boost Concussive Shot: Not Taken Frag Grenade: Rank 4 Damage, Rank 5 Max Grenades, Rank 6 Armor-Piercing Fitness: Rank 4 Durability, Rank 5 Shield Recharge, Rank 6 Fitness Expert

Equipment: Ammo: Cryo Weapon: Shotgun Rail Amp Armor: Cyclonic

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